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First English edition, 8vo (210 x 130 mm), lv, [1], 288pp., with the half-title, faint unobtrusive stamp to title page, 2 engraved plates, one folding table, some light browning and spotting, some minor water-staining more so to the last ten leaves, later maroon cloth, lower hinge torn. The French physician Philippe Pinel (1745-1826), who founded the French School of Psychiarry at Hospice de la Salp?triere, has been described as 'the father of modern psychiatry'. "Pinel was among the first to treat insane humanely; he dispensed with chains and placed his patients under the care of specially selected physicians. Garrison considered the above book one of the foremost medical classics, giving as it did a great impetus to humanitarian treatment of the insane."?Garrison-Morton. The first edition of his Traite medico-philosophique sur l'alienation mentale; ou la manie appeared in 1801. Provenance: Formerly in the library of the Birmingham Medical Institute. Hook & Norman, Haskell F. Norman Library II, 1704; Hunter & Macalpine, pp. 602-610; Garrison-Morton, 4922; Wellcome IV, p. 388.