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185649001(Paris, Mallet-Bachelier), 1856. 4to. No wrappers. In: ""Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences"", Tome 43, No 8 a. No. 10. Pp. (409-) 452 a. pp. (497-) 560. (Entire issues offered). Brown-Sequard's papers: pp. 422-425 a. pp. 542-546.
185649001Paris Mallet-Bachelier 1856. 4to. No wrappers. In: "Comptes Rendus Hebdomadaires des Séances de L'Academie des Sciences" Tome 43 No 8 a. No. 10. Pp. 409- 452 a. pp. 497- 560. Entire issues offered. Brown-Sequard's papers: pp. 422-425 a. pp. 542-546. <br/><br/><em>First appearance of a pioneering work in endocrinology initiating the development of our knowledge of the internal secretions."Brown-Sequard is best known for his research on the endocrine system the present work the papers offered being one of the most importent in that field. By the simple experiment of exicising the adrenal glands of animals he proved the glands were indispensable to life. It is one of the first works to demonstrate the functions of the glands of internal secretion and is basic to the development of endocrinology."Heirs of Hippocrates.Garrison & Morton No. 1140. - Heirs of Hippocrates No. 986. </em> unknown
20802Fort in-4° (263 mm) polycopié, demi-maroquin vert sapin, dos à quatre nerfs encadrant l’auteur et le titre dorés ; [11] ff. liminaires, 379 ff. recto, 5 planches hors-texte, 11 tableaux dont 9 dépliants et 12 planches de tirages photographiques originaux.
1987ZB394268S. Karger 1987-1998. volumes 25-27; 29; 31; 33-38; 41-47; 49-50. 1987-1998. partly bound library markings textually clean & tight PRICE IS FOR THE LOT. - If you are reading this this item is actually physically in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties taxes or fees required by recipient's country. Photos available upon request. S. Karger unknown
In 8° (15,4×9,6 cm); (16 compresa antiporta figurata), 168, (8) pp. e 4 c. di tav. Anatomiche delle quali 2 più volte ripiegate. Legatura ottocentesca in mezza-pelle chiara con tiolo, autore e filetti in oro al dorso. Piatti foderati da carta marmorizzata coeva. Qualche strofinatura e difetto. Due piccolo timbretti ottocenteschi al frontespizio che attestano come l’opera appartenesse alla collezione bolognese Magnanini e ceduto in quanto duplicato nel 1890. Un leggerissimo ed ininfluente alone al margine esterno alto del volume, spesso praticamente invisibile e nel complesso ininfluente e per il resto esemplare in buone-ottime condizioni di conservazione di questo importantissimo testo della storia della medicina endocrinologica, scritto dal grande anatomista e fisiologo svizzero, celebre per i suoi studi sul pancreas ed il duodeno, Johann Konrad Brunner (Diessenhofen 16 January 1653 – Mannheim 2 October 1727). Prima rara edizione, tre soli esemplari censiti in ICCU, di questo studio dedicato all’anatomia e fisiologia del pancreas. L’autore fu tra i primi ad avvicinarsi alla scoperta del diabete portando avanti esperimenti pionieristici sulle secrezioni pancratiche. Nei suoi esperimenti venne aiutato da un altro celebre medico svizzero, Johann Konrad Peyer che fu il primo a descrivere i follicoli linfoidi nel piccolo intestino nel 1677 e non a caso questo scritto contiene al suo interno anche una parte della corrispondenza fra Preyer e Brunner. L’autore studiò medicina a Schaffhausen, Strasbourgo, Amsterdam, Londra e Parigi. In particolare nei primi anni di formazione fu allievo di Johann Jakob Wepfer (1620-1695) che fra l’altro era anche il suo padrino. Conseguito il dottorato in medicina nel 1672 a Strasburgio. Dal 1686 ricoprì la prestigiosa cattedra di anatomia e fisiologia di Heidelberg. Nel 1716, Brunner venne nominato medico personale dell’Elettore del Palatinato, Carlo Filippo III. Nella sua vita ottenne numerossimi riconoscimenti e venne nominato anche cavaliere con il titolo di “Brunn von Hammerstein”. Prima rarissima edizione di un testo di grande importanza per la storia dell’endocrinologia e del diabete. First edition, a good copy. Rif. Bibl.: Foster, Lectures on the history of physiology, 162164. Wellcome II-258. Norman N° 362. Waller 1566.
190249356London, Harrison and Sons, 1902. 8vo. Contemp. full cloth. Top of spine worn down. Lower spine end with a small crack. A collation remark on title-page. A bookmark on inside frontcover, stating that the volume was bound 10/9/02 for City of Manchester. Municipal Technical School. ""Proceedings of the Royal Society"", Vol. 69. VII,501 pp. a. 6 plates. Bayliss & Starling's announcement: pp. 352-353. Internally clean.
190249356London Harrison and Sons 1902. 8vo. Contemp. full cloth. Top of spine worn down. Lower spine end with a small crack. A collation remark on title-page. A bookmark on inside frontcover stating that the volume was bound 10/9/02 for City of Manchester. Municipal Technical School. "Proceedings of the Royal Society" Vol. 69. VII501 pp. a. 6 plates. Bayliss & Starling's announcement: pp. 352-353. Internally clean. <br/><br/><em>This is the first printing annoucing a milestone discovery which introduced a quite new field in physiology and medicine the discovery of the FIRST HORMONE which the discoverers named "Secretin". A few years later Sterling coined the word 'hormone' from the Greek 'hormon' meaning to exite or set into motion. Until know it was though that the control of the glands here the pancreas was controlled by the nerves Pavlow and others but Bayliss and Sterling showed that they have found that the intestine was signalling the pancreas by some COMPLETELY NEW MECHANISM involving a new kind of body or substance functioning as a chemical messenger. "If nerves are the sprinters of biology Bayliss & Starling had discovered the marathon runners. In doing so they also founded the science of hormones called endocrinology" Alan Lightman "The Discoveries" p. 34 ff. The announcement as offered here was later the same year followed by their larger paper "The Mechanism of Pancreatic Secretion" which they published in "Journal of Physiology 1902"."With the discovery of hormones Bayliss & Starling had found the internal command and control centers - and in this their discovery was much larger than a new communication system. The mechanism of response and control was chemical: atoms and molecules. Now with hormones there was a mechanism for a living thing to regulate itself. Furthermore with hormones an organism could not only be studied but also controlled from the outside. Never had the living body come closer to a machine a self-regulating machine governed not only by physics but also chemistry. An not only a machine but a machine that we human could willfully control. At the start of the new century we still have not come to terms with the implications of this idea."Alan Lightman.Parkinson "Breakthroughs" 1902 B. </em> hardcover