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SNOW FLORENCE LABAA

SINCERELY YOURS

Snow JohnABAA

On the pathology and mode of communicaiton of cholera. In London Med. Gazette vol. 9

184945527London 1849. Snow John 1813-58. On the pathology and mode of communication of cholera. In London Medical Gazette n.s. 9 1849: 745-755; 923-929. Whole volume. 2 1129pp. Text illustrations. 214 x 133 mm. 19th century half calf cloth boards hinges split some wear. Internally very good. Library bookplates. First Edition journal issue. Snow first became interested in cholera at Newcastle-on-Tyne during the epidemic of 1831-1832 and recurrent outbreaks of the disease gave him the opportunity to investigate it in detail. His paper on cholera published shortly after his extremely rare 31-page pamphlet On the Mode of Communication of Cholera contained his first demonstration of the specific nature of the disease which he defined correctly as an infection of the alimentary canal transmitted by ingesting fecal matter from cholera patients in most cases via contaminated water. Snow proved his theory of cholera transmission by collecting data on a large number of outbreaks and correlating them to local water supplies. He argued based on his data that cholera was caused by "a specific living waterborne self-reproducing cell or germ" Dictionary of Scientific Biographyâ€”a conclusion all the more remarkable in that it predated the germ theory of disease by over a decade. Snow may have been motivated to contribute his paper to the London Medical Gazette because a review of his separately published pamphlet published in that journal on pp. 466-470 of the 1849 volume stated that he had not proved the contagious nature of cholera. Snow's theory of cholera transmission aroused much controversy among physicians many of whom still held the ancient belief that cholera and all other infectious diseases were carried by atmospheric "miasmas" emanating from noxious sources. Snow was vindicated a few years later however when during the great London cholera epidemic of 1854 he located the source of infection at the Bow Street pump and persuaded local authorities to remove the pump's handle causing a dramatic drop in the rate of infection. Snow's work on cholera greatly influenced sanitary reformers such as Sir Edwin Chadwick and provided critical support for the work of Pasteur and Koch in the 1860s and 1870s. Collectors of John Snow's work on cholera have tended to focus on and drive up the prices of his 1849 pamphlet and his 1854 book and to ignore the revolutionary conclusions that Snow drew in this paper of 1849. Garrison-Morton.com 5106. Shephard John Snow p. 303. . unknown books

Jeremy Norman & Co., Inc. · États-Unis3 750,00 $US≈ 3 172,88 €

SNOW John MRCS. 1813 1858. M. R. C. S.ABAA

On asphyxia and on the Resuscitation of Stillborn Children.

1842M13976Boston:: The Boston Medical and Surgical Journal vol. XXV no. 26 February 2 1842. 1842. 8vo. pp. 409-424. Disbound. Very good. RARE. First American issue. Also published "On asphyxia and on the resuscitation of still-born children" London Medical Gazette vol. 29 5 November 1841: pp. 222-27. / Between 1839 and 1841 Snow experimented with a guinea pig suffocating the creature and then beginning a dissection. He found that an hour after death that he perceived a "slight vermicular motion in the right auricle. He opened the trachea and began artificial respiration. The heart's ventricles began to move and through the coast of the left atrium the chamber that receives blood from the lungs he could see oxygen-rich bright red blood. The heart continued to contract weakly unable to expel blood from its chambers but it kept beating rhythmically for forty-five minutes. . . . This particular experiment took place in the course of his investigations into respiration and asphyxia undertaken with the desire to establish the physiological basis for pulmonary resuscitation on infants." Snow was witnessing one in twenty births being stillborn many of whom were asphyxiated. Many methods of resuscitating were tried including electrical shock mouth-to-mouth resuscitation etc. "Snow surmised that the line between life and death was not fixed and the heart retained its irritability its ability to be stimulated by oxygen beyond death." With this study done Snow's recommendation was to use his "artificial respirator on still-born infants." p. 1-3. This whole effort was to reinforce Snow's experimental method to study a medical problem. Because of this experience he was encouraged to continue his research practices. The announcement created a varied debate wherein many opinions and experiences were expressed. This led if indirectly to his use in 1848 to apply chloroform to a patient with a difficult birthing history. p. 4. â€“ Vinten-Johansen et.al. / "Shepard considers this paper particularly significant for Snow's later anesthesia research." By Peter Vinten-Johansen Howard Brody Nigel Paneth Stephen Rachman Michael Rip David Zuck Cholera Chloroform and the Science of Medicine: A Life of John Snow. Oxford University Press 2003. pp. 1-34 90-95. The Boston Medical and Surgical Journal, vol. XXV, no. 26, February 2, 1842. unknown books

Jeff Weber Rare Books · Suisse1 250,00 $US≈ 1 057,63 €

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